diff --git a/scripts/zig-cc b/scripts/zig-cc
index 4b1293dde..b6d9ebc68 100755
--- a/scripts/zig-cc
+++ b/scripts/zig-cc
@@ -5,6 +5,10 @@ import os
 
 
 def flag_filter(flag: str) -> bool:
+    # Workaround for <https://github.com/sfackler/rust-openssl/issues/2043>.
+    if flag == "-latomic":
+        return False
+
     if flag == "-lc":
         return False
     if flag == "-Wl,-melf_i386":
@@ -24,6 +28,11 @@ def main():
     else:
         zig_cpu_args = []
 
+    # Disable atomics and use locks instead in OpenSSL.
+    # Zig toolchains do not provide atomics.
+    # This is a workaround for <https://github.com/deltachat/deltachat-core-rust/issues/4799>
+    args += ["-DBROKEN_CLANG_ATOMICS"]
+
     subprocess.run(
         ["zig", "cc", "-target", zig_target, *zig_cpu_args, *args], check=True
     )